Botox Makes unnerving journey to CNS

Below article published in April 2015: “New research by the University of Queensland has shown how some of the potent toxin used for cosmetic surgery escapes into the central nervous system.”……”The discovery that some of the injected toxin can travel through our nerves is worrying, considering the extreme potency of the toxin,” researchers said.

While this article claims this is a new discovery….it in fact, is not. Evidence of botulinum toxin (ie Botox) entering the CNS was first published in the Journal of Neuroscience by a group of researchers at the Univeristy of Padova in 2008. That study was interpreted by other sources as being of no concern, citing the amounts used in the research were much larger than dosage amounts used in humans. Note, however, in the toxicity studies done by the manufacturer of Botox and not provided to the FDA, amounts used that killed half of the female subjects and caused systemic organ damage to all subjects were at dosage levels much lower than what is currently being given to children with limb spasticity.

What is significant about this new research is that it shows “escaping” single molecules of the toxin that are traveling at high speeds through the nervous system…and it takes just one single molecule of the toxin to permanently damage a neuron. While people receiving 25-50 units of Botox for cosmetic purposes may think that is a “miniscule” amount of toxin…..consider the fact that there are 20,000,000 molecules of toxin PER UNIT. And, no, the body does not “break down” these molecules and render them inactive. They remain active with a built-in “homing device” and target cholinergic nerve terminals throughout the body until they cleave and set off a chain reaction that permanently damages the proper functioning of the targeted nerve ending.

While the article claims that there are “no unwanted effects attributed to such transport has been reported…”, well, again….there were likely outside sources influencing that untrue statement. There are hundreds of published scientific articles that attest to distant spread of the toxin…..one of which was published in the Journal of Physcial Medicine and Rehabilitation in 2012 and specifically titled “Severe Nervous System Complications after Botulinum Type A Therapy”…..and cites patients that developed brain lesions after injections along with a review of the neurological adverse events as reported to the FDA between 1992 and 2009.

Let’s recap….the most toxic substance known to mankind (and no, Botox is not “purified” but in reality is even more lethal than naturally-occurring toxin given that it is stripped of protective proteins surrounding the toxic molecules)….researchers cite this discovery is “worrying”…….numerous published scientific articles on adverse events…..a Black Box warning issued….tens of thousands of reports to the FDA…..thousands more unreported…..people severely debilitated and reported deaths…..lawsuits filed and won and/or settled……BUT YET…..this drug is still deemed “safe.”

Botox makes unnerving journey to CNS

Botox Use Lawsuit History

Botulinum toxin type A is the active component in BOTOX® and BOTOX® Cosmetic. BOTOX® was FDA approved in 1989 for medical therapeutic use. The FDA approved BOTOX® Cosmetic in 2002 for the treatment of wrinkles known as the glabellar lines. Since being FDA approved, BOTOX® has been used for more and more medical conditions. In spite of the tens of thousands reports of adverse events after botulinum toxin injections, BOTOX® use is growing. Below is a report of some the lawsuits that have been filed regarding Botox:

In 2002, there was a case brought against Allergan from a woman who claimed that after a BOTOX® treatment for a then off-label use for migraines she developed unbearable migraine, fatigue, neck weakness and difficulties breathing and swallowing for four months. She lost her case against Allergan, but the company admitted that the product insert stated that BOTOX® had unknown risks as an anti-wrinkle treatment in doses higher than 20 units and acknowledged that the drug could spread to other areas of the body.

Allergan’s clinical studies had shown a potential link to headaches, pain, flu-like symptoms and respiratory problems. In 2005 a case of a death after a treatment with a BOTOX® -lidocaine mixture was reported for a woman being injected for chronic neck and back pain. It was felt at the time that she had an anaphylactic reaction to the lidocaine.

In 2006 there was a report of 4 adults who developed botulism after cosmetic injections. However, the botulinum preparation used reportedly was an unlicensed, highly concentrated mixture, and the patients received doses much higher than what is typically given.

In 2008, 15 BOTOX® users and their relatives sued Allergan claiming that the company failed to warn of the drug’s dangers. There were four deaths which included two children and two adults involving off-label use of the drug. The children received very high doses for limb spasticity related to cerebral palsy. One adult died from complications from injections for neck and shoulder pain, and one died from treatment for excessive salivation. Of the remaining eleven plaintiffs, the complaints were for droopy eyelids, numbness, headaches and swallowing and breathing difficulties. Three in this group had been treated for cosmetic reasons.

Later in 2008, a Consumer group called Public Citizen reported linking 16 deaths to use of botulinum toxin between 1997 and 2006. They also reported finding 180 adverse effects reported. This lead the FDA to do a Safety Review of BOTOX®, BOTOX® Cosmetic ( both botulinum toxin type A) and Myobloc® (botulinum toxin type B). The conclusion of the FDA Safety Review was reported in April 2009. It stated that the manufactures of botulinum toxin products must add a boxed warning about the risk of adverse events that may occur when the effects of the toxin spread beyond the injection site.

The FDA had received reports of systemic adverse reactions suggestive of botulism that would occur if the toxin spread beyond the injection site, including respiratory compromise and death, after use of these products for both approved and unapproved uses. The deaths in children occurred when treating limb spasticity associated with cerebral palsy. The adult cases had been also treated for spasticity and cervical dystonia. However, the adult cases of death could not be attributed to botulinum toxin, claiming “pre-existing conditions”. There had been reports of symptoms after cosmetic use, but the FDA claimed there were no definitive serious adverse event had been found with on-label use of BOTOX® Cosmetic.

In February 2010, a lawsuit was filed by a woman in Virginia who claimed that after being treated for head tremors with BOTOX® in 2008 she suffered brain injuries, movement disorders and dementia. She stated that she developed autoimmune encephalitis movement disorder. She alleged that Allergan failed to warn consumers that a side effect of BOTOX® can cause serious autoimmune responses, brain injury and botulism. The FDA “black box” warning about potential spread beyond the site of injection had been added in 2009. Her case settled out of court in October 2011.

In March 2010, Allergan was found not liable in the death of a 7 year old who died after being treated with BOTOX® for limb spasms caused by severe cerebral palsy.

In May 2010, a physician in Oklahoma sued Allergan stating that she suffered botulism poisoning after using 50 units of BOTOX® to treat wrinkles. Allergan was found negligent because the 2006 product labeling did not have adequate information about side effects. Another point made in that trial was the fact that Allergan had known about potential botulism dangers but had denied the connection in promotional materials to doctors and patients. An independent study commissioned by Allergan in 2007 found 207 adverse events being due to the spread of the toxin, including this plaintiff’s case. It was reported that Allergan had the study revised to show only 26 adverse event cases, eliminating any incident that had a plausible explanation other than an effect from BOTOX®.

In September 2010, Allergan settled a BOTOX® wrongful death lawsuit on behalf of a woman who died in 2008 after receiving 100 units to treat pain in her shoulder. The family claimed that the patient was never informed about the potential side effects before she was injected.

In April 2011, Allergan was sued by a Virginia man who claimed he developed brain damage after being treated with BOTOX® in 2007 for cramps and tremors in his hand. He claimed that Allergan failed to warn him that injections could trigger an autoimmune reaction leading to brain damage. Allergan claimed that the injuries weren’t caused by BOTOX® but by a pre-existing genetic stroke condition. During the trial, it came to light that in 2007 Allergan had sent European regulators a letter that contained warnings about BOTOX®, but had failed to do so in the U.S. market.

In 2013 an abstract was published by Dr. Anna Hristova titled “Neurological complications to botulinum toxin A therapy” published by the International Congress on Bacteriology & Infectious Diseaese. She suggests that there is evidence that the toxin can spread and cause clinical illness. She postulates that there can be CNS damage resulting in autoimmune encephalitis and persistent fatigue and lack of endurance, peripheral nervous system damage resulting in an autoimmune reaction such as Guillaine-Barre and small fiber polyneuropathy, and autonomic nervous system damage such as heart arrhythmias. She makes her claim based on personal experience, personal observation and a review of the literature. She also acknowledged that currently there are unfortunately no tools or methods to prove the causality of death or damage due to botulinum toxin type A.

In September 2011, Allergan settled a case of a San Francisco woman who had cosmetic injections and claimed to have developed systemic problems including weakness and fatigue.

In May 2012, a Missouri man settled a $60.5 million lawsuit with Allergan. He claimed he was diagnosed with Guillain-Barre Syndrome after having BOTOX® injections for back pain in 2008. Guillian-Barre Syndrome is a paralyzing condition that can occur after a viral illness. Allergan denied any awareness of the condition being caused by BOTOX®.

In April 2014, a physician who injected a patient for TMJ and migraines as well as cosmetic enhancements was sued for failing to adequately inform her of known serious and debilitating side effects of BOTOX®. She was injected with 75 units of BOTOX®. It was reported that she developed an acute severe immune reaction to BOTOX®, and that reaction resulted in permanent devastating injury to her. She gradually became worse and died. Allergan was not a party to the lawsuit.

In November 2014, two parents sued Allergan after their 7 year old son developed life-altering damage after BOTOX® injections in 2010 for leg spasms secondary to cerebral palsy. It was claimed that the boy suffered an allergic reaction leading to development of seizures. Though BOTOX® is not approved by the FDA for pediatric spasticity, the parents argued that Allergan did not properly warn the public of potential dangers of using the product. The family was awarded $6.75 million.

A literature review of peer-reviewed articles from 1988 until 2008 published in the Journal of Cutaneous and Aesthetic Surgery by HM Omprakash and SC Rajendran found two classes of adverse events reported: transient benign events and potentially serious events. Transient benign events, associated with smaller doses used for cosmetic treatments, included hematoma, injection site pain, intractable headache, ptosis, diplopia and hyperactivity of the local antagonistic muscle. The serious events suggestive of botulism-like symptoms were dry and red eye, accommodation difficulty, dry mouth, gastrointestinal disturbances, dysphagia, hoarseness and breathing difficulties.

Digestive problems and severe lower abdominal pain

I have these lower abdominal crises where it swells so bad that I look like a pregnant woman even though it’s not that much painful but then when the tightness starts to kick in all hell brakes loose .Feels like the colon is getting very tight to the point that effects breathing and also makes me almost pass out from pain .Been in chronic pain for so long I believe I can tolerate medium to high pain to certain extent but when this kinda pain hits  its just unbearable .I noticed that sometimes happens when I eat a food that I shouldn’t ,stress to much or over think but also other times for no apparent reason and was just wondering if anyone else had this happening and if anything was helpful for it.

Pls help me again and discuss your eye/ face symptoms…

So I am really starting to feel I have CRPS of the face/ eyes from the botox injury (I can have both). I ask CRPS victims and the symptoms line up, plus I know no matter what I do have that condition too elsewhere…If anyone has these symptoms that I have starred with ** I need to know, in case I am wrong.

CRPS evolves and spreads and these things are just getting worse. As some heard before, I am encouraged to do an intervention for CRPS after all (as of today) when symptoms took on a new level of scary. CRPS of eye can sometimes lead to blindness. It can lead to incredible lifelong eye pain. My left arm is affected by CRPS from a needle poke and it never improved in 2.5 years. But interventions have complications.

So, I want to hear again how closely your symptoms lineD up with mine and if it improved on its own.

Eyes

– extreme 10/10 eye pain like stabbing pressure in bavk of eye – goes on all day…worsens with light and eye movement** pain that is horrible after 2 10/325 norco amd 150 mg Lyrica for example

– blurry vision, floaters

– burning of eye **

– painful to blink

– dry eyes (also symptom of CRPS)

 

Face

– intense burning of face and chest which can suddenly spread to include scalp, and waxes and wanes**

– heat of face and upper chest comes with flushing of face, whole face darker color along with-  hest, face hot to touch – even like this on 150 mg lyrica **

– continued intense pain at unjection sure needle sites nearly two months out **

– jaw pain, ear pressure, tooth pain

– heightened sensitivuty to pain/ pressure

– intense headaches**

– burbing that jumps ahead to include mew areas and has a demarkation line where it ends

– normal eye exam except for early onset liquifaction

Drugs do not dampen symptoms.

thank you!

 

 

 

 

 

 

 

And we believe the FDA will respond to our reports of Iatrogenic Botulism….

I am so discouraged by continuously reading articles reiterating what we already know about the FDA regarding patient safety.
Beware FDA ‘Approved’ Robotic Prostatectomy Care
Mon, 05/18/2015 – 1:24pm
PR Newswire

A South Florida-based urologist today has issued a stinging report critical of the Food and Drug Administration (FDA) decision to approve robotic surgery for treating prostate cancer on the basis of only some low-level and irrelevant gallbladder studies.

Dr. Bert Vorstman is a proponent of focal therapy in certain cases of prostate cancer and his dire warnings regarding the misrepresentations, lack of ethics and chicanery surrounding the robotic prostatectomy have been echoed by a number of physicians and organizations.

Said Dr. Vorstman, “Not only has the healthcare public been totally duped into thinking that robotics have been scientifically proven to be safe and effective in the treatment of prostate cancer (when it has not) but the robotic prostatectomy is commonly used to treat the Gleason 3+3=6 ‘cancer’ which lacks the hallmarks of a cancer. In essence, many men are treated for a disease, which needs no treatment, undergo surgery with an unproven device and are often left limp and leaking.”

In his report, Dr. Vorstman added, “The dangers of the robotic prostatectomy are clearly evidenced by the endless lawsuits filed against surgeons and the device manufacturer; the scores of self-reported harms listed on the FDA’s own product safety system, MAUDE (Manufacturer and User Facility Device Experience) representing only about 8% of actual adverse events, as well as the warnings issued by the USPSTF (U.S. Preventive Services Task Force), a Government oversight agency and the robot makers themselves who clearly recognize the device dangers as their disclaimers are getting longer with each revision.”

Dr. Vorstman continued, “The intentional withholding of information, deceptions, and distortions regarding the radical prostatectomy being perpetrated now by robotics advocates know no bounds. Even worse than the approval of robotics for treating prostate cancer without a single case of prostate cancer ever being tested for that study was the recent shameful FDA denial of the high-intensity-focused-ultrasound (HIFU) application. For this HIFU device evaluation, emboldened FDA urology panelists protected their approved robotic prostatectomy franchise even further by conjuring up trial criteria ensuring the HIFU application would fail.”

Furthermore, said Dr. Vorstman, “Embarrassingly, some urologists have stooped even lower recently by exploiting the medical illiteracy of Senate Staff for a political pushback on the USPSTF to discredit its ‘D’ grading of PSA-based prostate cancer screening and their conclusion that screen-detected prostate cancer treatment benefits are outweighed by the harms.”

Dr. Vorstman warned, “The FDA is responsible for protecting the public health by assuring the safety of medical devices. However, when powerful urologists are able to penetrate the nation’s oversight agencies and exert influence to satisfy self-serving needs, it signals a dangerous failure of regulatory oversight. Sadly, the need to protect a surgical ‘truth’ which only urologists can see, has trumped patient safety in favor of profit.”

Weekend retreat or Informal conference

I was talking with another member from the site yesterday. She mentioned that maybe we should organize a weekend retreat or informal conference for the support group members well enough to attend. We could get together to discuss experiences,treatments and ways to raise awareness of Botox poisoning. We don’t know where this would be held, but we were thinking maybe somewhere centrally located? Somewhere tropical would be good,too!lol Please respond with your thoughts on this? Would anyone be interested?

f.lux for eyes

hey everyone i posted about this before but given the amount of talk about eye issues lately and a lot of peopel having difficulty with their eyes im mentioning it again: there is a small program called f.lux which automatically dims the light of your computer monitor according to the time of day. it can be downloaded easily here if you run windows or mac : https://justgetflux.com/

i seriously cant use a normal computer screen now it makes me feel like my eyes are melting. i know all of us use the computer and this little program has been a lifesaver in many ways. it really reduces eye strain… as well as helping with issues like insomnia or sleep problems related to blue light exposure in the evening.

it is better than just adjusting your monitor it actually changes the light to more red than blue on the color spectrum. i really recommend it for people with any kind of eye/light sensitivity.. since all of us use computers. its extremely simple to download and run.

oh: in case you are wondering what it actually looks like, just imagine looking at a white page on your screen and then like turning a dial that makes the screen much much darker, and a warmer tone of light, less eyeball meltingly blue. we get so used to electronic light being blue we dont notice it. but once you get used to a more ‘warm’ tone of light in your monitor, you will never want to go back. (i didnt anyway) its like looking at parchment instead of neon.

light at the end of the the tunnel

I want to share my Botox experience with everyone because I am living proof that there is a light at the end of the tunnel.  I had 100 units of Botox injected into my right pirirformis muscle for piriformis syndrome.  I had been experiencing unbearable sciatic pain for years and my doctors and therapists suggested the injection.  I am an RN and was concerned about injecting a toxin into my system, but was assured by my doctor that it would wear off within 3-4 months; the worst I might experience is mild flu-like symptoms.  As we all know, this is simply not true. My injection was on March 20, 2014 and I have experienced the following symptoms over the past 14 months:  anxiety, depression, short term memory loss, severe diarrhea, fatigue, headaches, hypertension, night sweats, swallowing problems, internal chills, paleness, visual problems, ringing in ears, episodes of paralysis to all 4 extremities, with the inability to hold up my head, severe breathing problems, slurred speech and droopy eyelids.  I have been in and out of numerous hospitals over the past 5 months.  All tests have come back negative. My pain management doctor, who is new to me, was the only doctor to acknowledge that my symptoms are most likely due to the Botox injection.  From what I understand, there is no cure.  I have a wonderful primary are physician who is treating my symptoms; and mine have improved significantly over the past few weeks.  I take Propranolol 10mg in the morning and 20mg at bedtime.  I also take Klonopin 0.5mg twice a day. These meds were initially prescribed for hypermobility syndrome, but they also seem to be managing my Botox symptoms, as well.  My diet consists of fresh fruits, vegetables, small amounts of lean meat, Bolthouse smoothies with added protein supplement;  I drink a lot of water and have eliminated alcohol and soda and I limit my sugar intake.  I also take a probiotic twice a day; the diarrhea has resolved.  I had been confined to a wheelchair, but I am not able to walk short distances, and I will begin aquatic PT soon.  Pulmonary function tests revealed that my small airways are only functioning at 58%.; however, I have learned to pace myself, going up and down the stairs only a few times a day.  I have oxygen as needed, but thank God I haven’t needed to use it much.  I feel I am getting stronger every day.  This experience has had a positive outcome for me because it has renewed my faith in God.  I have been praying daily and I am now attending church regularly with my family.  I truly believe in the power of prayer and I thank God every day that I am alive and that I am getting better.  I pray for everyone who is enduring this nightmare.  But please, keep the faith that things will get better.  God Bless.

fully devastated

Hi.

Im from poland and my english is not perfect. Sorry for any grammar mistakes.

Im 6 months after my botox injection.

 

Now i look like no longer me.

I look strange…odd… my face looks horrible.

Different shape of my eyes, enlarged eyebrow muscles, strange smile (droop mouth).

My face looks like a big puffy balloon (swelling??).

This is like never ending nightmare.

I have 5 years old daughter. Im depressed.

I have zero quality of life.

My face changes 50 times a day.

One thing im perfectly sure… this is not my face.

Not my fucking face.

 

Numbness with tongue and mouth

Hi all-

has anyone had tongue numbness or on the inside of your mouth? I pretty much associate all my symptoms to Dysport but I’m not sure if I’ve seen anyone posted about this but it would make sense if this was caused by the poisoning.  It’s really the least of my symptoms but I’m guessing because I know 2 people who had cancer recently and one of their earlier symptoms was tongue numbness.

Thanks!

4 weeks now Bladder retention

Update the hives, sore throat and blocked ears are gone. Tightness by right eye still and I just looked off. Today woke up and now am having urinary retention Having difficulty emptying bladder and weak flow. This has never been a problem before Can this honestly be from cosmetic botox? And a whole month after? I just want to stop being scared.

Botox and Juvaderm nightmare

Hellish existence..onset 5 days after Botox injections. I have been getting Botox since 2007. Over the years I had some strange symptoms..like eating and all of a sudden when I go to swallow the soup..nothing happens so I sit with soup in my mouth in a frozen state and then soon can swallow. I thought it was the onset of some horrible future disease. It never occurred to me could be the Botox. Anyhow..last time I had Botox March 27, doctor seemed to put it almost direct into my temples..she was in a hurry that day.I also had Juvaderm injected around my mouth, sides of mouth, chin area. I thought nothing of it. In the next 5 days I developed numb , tinglling , pins and needles in fingers. Over the past month and  a half this has progressed to my feet and my tongue and lips,mouth area. My hands feel like they were stung by a jellyfish and flash seared in pan with hot oil and are stiff feeling. I can no longer text..too painful. I have been to the ER , a neurologist, a rheumatologist, an internist. Had an MRI of brain, MRI of neck, 64 slice CT scan and many many blood tests and nothing they checking for allthings like MS, etc. etc. and there is nothing found they can attribute to this. The neurologist is the only one that admitted it could be the Botox.
it should be the makers of Botox and/or Juvaderm proving to us it is not the Botox…not us having to prove to them it is…I can barely perform my work functions due to the pain and burning and neuropathy in hands..cannot taste food right…wearing flip flops as shoes too painful. Suddenly out of the blue..I get like this? no explanation? no traceable reason?

Botox and Juvaderm neurological nightmare

Hellish existence..onset 5 days after Botox injections. I have been getting Botox since 2007. Over the years I had some strange symptoms..like eating and all of a sudden when I go to swallow the soup..nothing happens so I sit with soup in my mouth in a frozen state and then soon can swallow. I thought it was the onset of some horrible future disease. It never occurred to me could be the Botox. Anyhow..last time I had Botox March 27, doctor seemed to put it almost direct into my temples..she was in a hurry that day. I thought nothing of it. In the next 5 days I developed numb , tinglling , pins and needles in fingers. Over the past month and  a half this has progressed to my feet and my tongue. My hands feel like they were stung by a jellyfish and flash seared in pan with hot oil . I can no longer text..too painful. I have been to the ER , a neurologist, a rheumatologist, an internist. Had an MRI of brain, MRI of neck, 64 slice CT scan and many many blood tests and nothing they can attribute to this. The neurologist is the only one that admitted it could be the Botox. check this out http://www.newsweek.com/new-reason-frown-85491
it should be the makers of Botox proving to us it is not the Botox…not us having to prove to them it is…I can barely perform my work functions due to the pain and burning and neuropathy in hands..cannot taste food right…wearing flip flops as shoes too painful. Suddenly out of the blue..I get like this? no explanation? no traceable reason?

Hellish existence after Botox and Juvaderm injections

Hellish existence..onset 5 days after Botox injections. I have been getting Botox since 2007. Over the years I had some strange symptoms..like eating and all of a sudden when I go to swallow the soup..nothing happens so I sit with soup in my mouth in a frozen state and then soon can swallow. I thought it was the onset of some horrible future disease. It never occurred to me could be the Botox. Anyhow..last time I had Botox March 27, doctor seemed to put it almost direct into my temples..she was in a hurry that day.Also I had Juvaderm around my mouth, sides of mouth and on chin. I thought nothing of it. In the next 5 days I developed numb , tinglling , pins and needles in fingers. Over the past month and  a half this has progressed to my feet and my tongue and lips. My hands feel like they were stung by a jellyfish and flash seared in pan with hot oil . I can no longer text..too painful. I have been to the ER , a neurologist, a rheumatologist, an internist. Had an MRI of brain, MRI of neck, 64 slice CT scan checking for MS, Lupus, etc. etc. and many many blood tests and came back normal and showing nothing they can attribute to this. The neurologist is the only one that admitted it could be the Botox. check this out http://www.newsweek.com/new-reason-frown-85491
it should be the makers of Botox proving to us it is not the Botox…not us having to prove to them it is…I can barely perform my work functions due to the pain and burning and neuropathy in hands..cannot taste food right…wearing flip flops as shoes too painful. Suddenly out of the blue..I get like this? no explanation? no traceable reason? What about a Botox / Juvaderm combo exacerbating the other? Not sure what is going on ..but I truly feel as though I have been poisoned.

Hellish existence

Hellish existence..onset 5 days after Botox injections. I have been getting Botox since 2007. Over the years I had some strange symptoms..like eating and all of a sudden when I go to swallow the soup..nothing happens so I sit with soup in my mouth in a frozen state and then soon can swallow. I thought it was the onset of some horrible future disease. It never occurred to me could be the Botox. Anyhow..last time I had Botox March 27, doctor seemed to put it almost direct into my temples..she was in a hurry that day. I thought nothing of it. In the next 5 days I developed numb , tinglling , pins and needles in fingers. Over the past month and  a half this has progressed to my feet and my tongue. My hands feel like they were stung by a jellyfish and flash seared in pan with hot oil . I can no longer text..too painful. I have been to the ER , a neurologist, a rheumatologist, an internist. Had an MRI of brain, MRI of neck, 64 slice CT scan and many many blood tests and nothing they can attribute to this. The neurologist is the only one that admitted it could be the Botox. check this out http://www.newsweek.com/new-reason-frown-85491
it should be the makers of Botox proving to us it is not the Botox…not us having to prove to them it is…I can barely perform my work functions due to the pain and burning and neuropathy in hands..cannot taste food right…wearing flip flops as shoes too painful. Suddenly out of the blue..I get like this? no explanation? no traceable reason?

 

 

Post April 2 Injection Photos

 

One day before injections
2011
December 2014 Dickens Faire
December 2014 Dickens Faire

 

image
Before, 2012

 

 

 

 

image
Before, one day before injections, no makeup.

Flushed hot face last weeken.

Now, last weekenf, facial swelling, redness.
Now, last weekenf, facial swelling, redness.

 

Flushed hot face

 flushed hot face

image image imageimage

 

image image

image

One of the first days
One of the first days

image

 

While I was on steriods- functioning.
While I was on steriods- functioning.

image

 

These are just symptom photos from after April 2, 2015.

 

I know people post their symptoms but I specifically need to know if anyone is experiencing:

– heat/ temperature changes in their fave or elsewhere that go back to normal. Does your face get hot and flushed for a day then cool down again?

– skin sensitivuty to clothes and pressure, skin color changes like redness, blueness, mottling

these are typically CRPS symptoms and I wonder if ai habe CRPS of the upper thigh and face too. Or whether it will go away & it’s just botox.

Iron level jumps

Since I became so ill my iron level droped below minimum level , the norm in Poland is 37-145, mine was 35 then it jumped to 165 in just one month. Now it is again below minimum. Do u guys have or had problems with Iron? Why it gets so low? I never had this problem before injection.